Dr. Charu Thapliyal

Dr. Charu Thapliyal, Assistant Professor


Faculty Photo Faculty Details
  • Education: Ph.D.
  • Email: charuthapliyal@doonuniversity.ac.in
  • Area of Specialization/Interest: Protein aggregation and amyloid disorders, Chaperone-assisted protein folding, neurodegenerative diseases.
Detailed Profile IRINS Profile
Awards & Honours:
  1. SERB-funded National Post-Doc Fellow (2017-19)
  2. DST-funded Women Scientist A (2019-22)
  3. DST-funded Women Scientist A (2023-25)
  4. ICMR Postdoctoral Research Associate, Govt. of India (Not availed).
  5. ANRF International Travel Support (ITS) and DBT-CTEP Travel Grant, awarded for presenting research work at the Biophysical Society Annual Meeting, San Francisco, USA.
  6. Participation in Sokendai Asian Winter School “Basics and Frontiers in Molecular Sciences,” fully funded by the Institute of Molecular Sciences, Okazaki, Japan.
Best Five publications in last five years:
  1. Charu Thapliyal* and Rajesh Mishra*, ‘The Chaperone-Active State of HdeB at pH 4 Arises from Its Conformational Rearrangement and Enhanced Stability Instead of Surface Hydrophobicity’ (2024) Biochemistry ACS 63 (9), 1147-116 (ISSN: 0006-2960) (* Corresponding author).
  2. Charu Thapliyal, Prachi Joshi, Masochon Raingam and Rajesh Mishra, ‘Lacmoid-Induced Conformational Changes Inhibit Fibrillation of Human Islet Amyloid Polypeptide’ (2025) ChemBioChem, 26 (17) e202500383 (ISSN:1439-7633).
  3. Charu Thapliyal, Neha Jain, Naira Rashid, and Pratima Chaudhuri (Chattopadhyay), ‘Kinetics and thermodynamics of the thermal inactivation and chaperone assisted folding of zebrafish dihydrofolate reductase’ (2018) Archives of Biochemistry and Biophysics, 637, 21-30 (ISSN: 0003-9861).
  4. Charu Thapliyal, Neha Jain, and Pratima Chaudhuri, ‘Investigation of folding, unfolding process of a new variant of Dihydrofolate reductase protein from Zebrafish’ (2016) International Journal of Biological Macromolecules 91, 736-743 (ISSN: 0141-8130).
  5. Naira Rashid, Charu Thapliyal and Pratima Chaudhuri (Chattopadhyay), ‘Osmolyte induced enhancement of expression and solubility of human dihydrofolate reductase: An in vivo study’ (2017) International Journal of Biological Macromolecules 103, 1044-1053 (ISSN: 0141-8130).